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phenobarbital will reduce the level or influence of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Potent or moderate CYP3A4 inducers may possibly enhance fee of diazepam elimination; as a result, efficacy of diazepam could be diminished.Barbiturates are respiratory depressants, along with the degree of